List - Science Center
The Science Center Research Park encompasses nearly two million square feet of space dedicated to the advancement of life science and technology companies. Of the two million square feet, more than 50,000 square feet are dedicated to incubator space providing fully equipped laboratories and "plug n' play" offices for entrepreneurs.
Current residents of the Science Center Port Business Incubators:
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Biologistics Consulting
Biologistics Consulting is an independent consulting firm specialized in the medical device, biotech and pharma industry. We partner with our clients to: 1.- Expand their business and identify highest potential opportunities. 2.- Optimize their supply chain. We offer to our clients a neutral and objective approach which sets up apart from main service providers. Our services are proposed from our offices in the US (Philadelphia) and in the centre of Europe near Brussels (Liège, Belgium)
www.biologistics-consulting.com -
Biomedical Research and Education Foundation (BREF)
Biomedical Research and Education Foundation (BREF) produces objective expert evaluations on biomedical technology and supports novel biomedical research and education that increases the understanding of technology by physicians, patients, and investors.
www.brefnet.org -
BioNanomatrix
BioNanomatrix is developing unique nanoscale imaging and analytic platforms designed to dramatically reduce the time and cost needed to analyze the genome. The company’s technology delivers comprehensive analyses of DNA and other genome-related peptides and proteins with single-molecule sensitivity while avoiding the fragmentation and complex data reassembly required by many other approaches.
The affordability, speed and simplicity of this technology are expected to make the routine use of genetic information feasible in broad-ranging applications including genetic diagnostics, personalized medicine and biomedical research.
www.bionanomatrix.com -
Calder Server Systems
Calder Server Systems assists a variety of financial organizations in the end-to-end delivery of differentiable and profitable wealth management services to their high-end clients via a mix of proprietary service management software and business consulting.
www.caldersystems.com -
Daedalus Innovations LLC
Daedalus Innovations develops tools and methods that expand the capabilities of NMR spectroscopy, which is a principal tool in structural and rational drug design. Detailed structural information about protein-ligand interactions and more recently membrane proteins has become some of the most valuable data for industrial applications. Current x-ray crystallography has failed to deliver on its promise to make study of these molecules routine. Daedalus Innovations tools will increase the impact of structural biology in the drug discovery process.
www.daedalusinnovations.com -
DMX Bio, Inc.
DMX inc develops novel techniques to generate vaccines against different infectious diseases:The Sterne vaccine strain is a severely attenuated Bacillus anthracis variant that naturally lost the capsule- encoding pXO2 plasmid and has been used as an effective animal vaccine worldwide for decades and possesses an excellent safety record.
www.dmx.com -
ERAI
Created in 1987, ERAI’s main mission is to help the companies of the Rhône-Alpes region to export and promote the local competences and know-how at an international level. Since then, ERAI has supported more than 4,000 companies. Each year, ERAI assists more than 1,000 Rhône-Alpes SME’s, provides 300 firms with personalized support through its agencies over the world, helps 200 firms to find international funding solutions and works closely with more than 22,000 business contacts worldwide.
www.erai.org -
ERYtech Pharma
ERYtech Pharma is a French biotechnology company specialized in the encapsulation of therapeutic molecules or enzymes into red blood cells. ERYtech Pharma offers innovative therapeutic solutions that harness the physiological properties of red blood cells to significantly improve the therapeutic index of the encapsulated molecules or enzymes. With its primary focus on oncology, ERYtech Pharma aims at developing products which offer better patient comfort, reduced side effects and improved efficacy.
www.erytech.com -
Gadore Center USA
Gadore Center USA services are oriented to the special requirements and demands of small and medium-sized companies scouting their opportunities in the North American market.
www.gadorecenter.com -
H&T Corporation
H&T Corporation focuses on the research and development of its TOX- LAUNCHER System, a software package that offers assistance in the management of preclinical safety tests necessary for pharmaceutical drug development.
www.ht21.co.jp/english/enews/information.html -
Integral Molecular
Integral Molecular develops novel technologies to enable the discovery and development of drugs that target integral membrane proteins, which are involved directly or indirectly in most major diseases, and comprise nearly half of all existing drug targets, including G protein-coupled receptors (GPCRs) and ion channels.
www.integralmolecular.com -
Integromics, Inc.
Integromics provides state-of-the-art Bioinformatics software solutions for data management and data analysis in Genomics, Proteomics and Drug Discovery. The company’s advanced software technology enhances the ability to effectively organize data, perform validated analyses, discover new biomedical knowledge and gain unique well-founded insights.
www.integromics.com -
Invisible Sentinel
Invisible Sentinel provides an alternative method to identify and control the consumption of pathogenic bacteria. It would serve as a powerful diagnostic tool for manufacturers, producers, distributors, retailers and ultimately the consumer.
www.invisiblesentinel.com -
iPRAXIS
iPRAXIS is a non-profit organization dedicated to accelerating the flow of knowledge, innovation and business between the people living in Philadelphia’s underserved communities and the city’s renowned academic research institutions and numerous cutting-edge life science and technology companies. It is our belief that by having access to the appropriate resources, more of the city’s minority residents will qualify for business and job opportunities in the sciences. We currently work with students in the middle schools and introduce them to the wonderful world of science. We have mentors we call ‘scienteers’ who work with the students and create science fair projects.
www.ipraxis.org -
Kayentis
Kayentis is the leading provider of Digital Pen & Paper solutions for the clinical trial industry. The Clin’Form® solution improves data collection and processing solution, by equipping all actors (laboratories, physicians, patients) with a simple and innovative tool: digital pen and smart paper. Fulfilling the requirements in terms of lawful conformity, traceability and data security, Clin’Form provides data sharing and processing via a secured web portal.
www.kayentis.com -
Meidlinger Partners
Meidlinger Partners, LLC is a
www.meidlingerpartners.net -
National University of Singapore’s (NUS)
National University of Singapore’s (NUS) Overseas Colleges program is a unique internship and immersion program with a strong emphasis on technology entrepreneurship; where a highly selected group of students will get to intern with (bio) technology start-ups within Philadelphia, while taking part-time courses at the University of Pennsylvania.
www.overseas.nus.edu.sg/noc -
Nuvon, Inc.
Nuvon’s patent-pending VEGA (Vectored Event Grid Architecture) platform enables timely, complete, and accurate access to point-of-care medical devices and patient care data from any location to communicate without barriers. Nuvon’s distributed system architecture spans disparate devices, networks, and protocols through an integrated system of intelligent and independently programmable appliances.
www.nuvon.com/ -
Opulus, Ltd.
Opulus, Ltd. is a biotechnology company focused on the development of revolutionary new measurement systems based on hyphenated Quartz Crystal Microbalance for molecular biology, drug discovery, and the development of new materials for drug delivery and advanced cosmetic treatment based on high resolution visco-elastic kinetics and in-situ cytotoxicity.
www.opulus.com -
Perfect Expressions Company
We aim to commercialize a new technology to rapidly sequence DNA. This technology can be applied (with proper preprocessing steps) to whole genome sequencing, and other assays including transcriptomics, transcription factor activity, miRNA expression, DNA methylation, and SNP analysis. DNACount measures the actual concentration of each gene by isolating, amplifying and sequencing each individual molecule in a high throughput manner.
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PKPD Incorporated
PKPD Incorporated is an advanced drug modeling and clinical trial simulation company, specializing in the development of optimal dosing regimens for the pharmaceutical and biotechnology industries. The company utilizes cutting edge, computer-based drug modeling and clinical trial simulation techniques to develop optimized dosing regimens during pre-clinical and clinical drug development.
www.pkpdinc.com -
Pulsar Informatics
Pulsar Informatics is conducting leading edge research in the field of human cognitive performance in collaboration with world-renowned research institutions. Applying modeling, signal processing and control system theory, we are translating this research into a set of technologically advanced tools for industrial and laboratory operations.
www.pulsarinformatics.com -
R&D Green Materials
R&D Green Materials is committed to developing innovative processes and technologies that will enable biobased plasties to be economically and structurally competitive with their synthetic counterparts.
www.randdgreenmaterials.com -
ReGenX BioSciences
ReGenX’s technology platform derives from discoveries in the laboratory of Professor James M. Wilson, M.D., Ph.D. at the University of Pennsylvania that led to identification of at least 30 new serotypes of adeno-associated virus (AAV). Several of these novel serotypes, including AAV7, AAV8, and AAV9 have emerged as vectors for gene delivery which are dramatically more efficient than previous serotypes. The ReGenX AAV Vector Technology enables the efficient, rapid, safe and specific delivery of genetic material into cells. Once delivered into a cell, the genetic material can use the existing cellular machinery to produce specific proteins encoded by the genetic material.
http://www.regenxbio.com/ -
Royal Society of Chemistry
The RSC is the largest organisation in Europe for advancing the chemical sciences. Supported by a worldwide network of members and an international publishing business, our activities span education, conferences, science policy and the promotion of chemistry to the public.
www.rsc.org -
Sunstone BioSciences, Inc.
Sunstone BioSciences, Inc. , in conjunction with Princeton University, National Cancer Institute and the University of Pennsylvania, are seeking to discover non-invasive techniques for treating cancer.
www.sunstones.com
In Vitro - PDT with up-converting nanoparticles shows complete cell kill for mesothelioma and bronchioloalveolar lung cancer cell lines.In Vivo - “Upon treatment utilizing external infrared excitation of a currently FDA-approved photosensitizer, mouse lung cancer models showed little or no evidence of tumor growth.”- University of Pennsylvania
Sunstone Nanoparticles are rare-earth oxide and oxysulfide nanocrystals that absorb electromagnetic energy at specific wavelengths and convert it to photons at different energy levels. Micron sized particles have been used for security applications for many years. The ability to produce the particles on a nano scale opens endless possibilities for In-Vitro and In-Vivo medical applications. Sunstone BioSciences, Inc. is currently developing up-converting nanoparticles as photosensitizer delivery and activation systems that will allow for preferential tumor uptake and provide greatest tumor destruction -
The Charlesworth Group (USA)
The Charlesworth Group (USA), Inc are a publishing services company, part of The Charlesworth Group www.charlesworth.com, with offices in the UK and China. We offer rights and licensing solutions as well as specialist marketing techniques for the fastest growing market in the world, China. We also provide cutting edge typesetting techniques and workflow consultancy, including a ‘Green’ Publishing program. We have developed unique XML pagination software, which can publish scientific and technical papers online and in print extremely quickly (within 10 minutes from styled Word document to formatted page proofs to authors). Our extensive client base is made up of universities, not-for-profit organizations, research centers, charities, government departments, trade associations as well as global organizations, and world leading publishers. Our goal is to disseminate information and broker relationships and cooperation, while helping academic and scholarly publishers/societies develop additional revenue streams and cost saving efficiencies.
www.charlesworth.com -
University City Keystone Innovation Zone
KIZs are a major initiative of Governor Edward G.Rendell to build knowledge-based economies and cultivate entrepreneurship in Pennsylvania. The idea behind the KIZ program is to create the necessary support networks within existing communities to maintain and grow the pipeline of budding innovators and dynamic new companies that will help shape the future of Pennsylvania’s economy.
www.uckiz.com -
Vector Biolabs
Vector Biolabs is a biotechnology company focused on developing robust gene delivery products, by using its proprietary technologies. The company’s products are highly valuable for scientific research, target identification and drug development.
www.vectorbiolabs.com
Incubator support companies located at the Science Center include:
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BioAdvance
BioAdvance provides funding to startup life sciences companies in Southeastern Pennsylvania through its $20 million Greenhouse Fund. We invest in therapeutics, devices, diagnostics and platform technologies focused on human health. Since its inception in 2002, BioAdvance has become one of the nation's leading investors providing pre-seed and seed-stage funding.
www.bioadvance.com -
Robin Hood Ventures
Robin Hood is a group of experienced entrepreneurs and accredited investors interested in investing and taking an active role in early stage companies with high return on investment potential. We focus on investing in early stage companies located in the Mid-Atlantic region, primarily scalable companies with intellectual property. Since our inception in 1999, Robin hood Ventures has invested in more than 28 companies.
www.robinhoodventures.com
Other traditional residents of the Science Center campus include:
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Alumifuel
AlumiFuel Power, Inc. (API) is a Philadelphia-based early production stage alternative energy company that generates hydrogen gas and steam for multiple niche applications requiring on-site, on-demand fuel sources. API’s hydrogen drives fuel cells for back-up and portable power, fills inflatable devices such as weather balloons, and can replace costly, hard-to-handle and high pressure K-Cylinders; its steam/hydrogen combination also drives turbine-based underwater propulsion systems and auxiliary power systems.
www.alumifuelpowerinc.com -
Avid Radiopharmaceuticals
Avid Radiopharmaceuticals is a product-focused molecular imaging company that is a pioneer in developing radiopharmaceuticals for imaging brain diseases. Through the use of targeted molecular imaging agents, Avid seeks to provide physicians with the tools to detect the first stages of pathological change, allowing early treatment and management of people at risk.
www.avidrp.com -
Chameleon Optics, Inc.
Chameleon Optics develops proprietary optical coatings based on electrochromic nano-particles. The major thrust of this variable-tint technology is energy conservation, i.e. electrochromic window film. However, these materials are the basis for a broad range of other products, including flexible displays, tunable eyewear, automotive visors, decorative/privacy films, and smart touch switches.
www.electrochromicink.com -
Rosetta Genomics Ltd.
Rosetta Genomics is a leading developer of microRNA-based diagnostic tests and therapeutic tools. MicroRNAs (miRNAs) are a recently discovered group of short (21–23 nucleotides in length), non-coding genes which regulate the expression of other genes. MicroRNAs have also been shown to have varying expression levels across various pathological conditions, and offer a new class of highly sensitive and tissue specific biomarkers. MicroRNA-based diagnostics may offer physicians and patients an objective tool to accurately identify cancer, predict outcomes and help guide treatment.
www.rosettagenomics.com