Nicholas A. Kefalides, 86, of Merion, a physician, a groundbreaking scientist, and an educator, died Friday, Dec. 6, at his home from complications of pulmonary fibrosis. Dr. Kefalides was emeritus professor of medicine at the University of Pennsylvania, and remained active until his final days as a member of the medical school's admissions committee. In 1970, he began what would become a 43-year career at Penn and a high-profile role as a pioneer in the study of the extracellular matrix - components of the body that fill the space between structured cells. He identified three novel components of the matrix, including a new subtype of collagen, which he labeled Type IV. Read more Article written by: Bonnie L. Cook, Inquirer Staff Writer